Glaucoma, a leading cause of blindness, often has a strong genetic component. Understanding hereditary risk factors can help with early detection and prevention. Here are key genetic and hereditary risks associated with glaucoma:
- Family History: Individuals with a parent or sibling who has glaucoma are 4 to 9 times more likely to develop the condition.
- MYOC Gene Mutation: Linked to primary open-angle glaucoma (POAG), this gene affects eye pressure regulation.
- OPTN Gene Variation: Associated with normal-tension glaucoma (NTG), causing optic nerve damage without high pressure.
- CYP1B1 Gene Mutation: A major cause of congenital glaucoma in infants.
- LOXL1 Gene Polymorphisms: Increase the risk of exfoliation glaucoma, which leads to blocked eye drainage. For more info - https://healthywz.com/genetic-and-hereditary-risks-of-glaucoma/